Human Genetic Modification
Human genetic modification (or “gene editing”) can be used in two very different ways. Somatic genome editing changes the genes in a patient’s cells to treat a medical condition. A few gene therapies are approaching clinical use but remain extraordinarily expensive.
By contrast, heritable genome editing would change genes in eggs, sperm, or early embryos to try to control the traits of a future child. Such alterations would affect every cell of the resulting person and all subsequent generations.
For safety, ethical, and social reasons, heritable genome editing is widely considered unacceptable. It is prohibited in 70 countries and by a binding international treaty. Nevertheless, in 2018 one scientist announced the birth of twins whose embryos he had edited. This reckless experiment intensified debate between advocates of heritable genome editing and those concerned it could exacerbate inequality and lead to a new, market-based eugenics.
Genome editing is a way of making changes to specific parts of a genome. Scientists have been able to alter DNA...
Public and policy conversations about heritable human genome editing often leave the impression that rules governing it are few and...
KPIX 5 CBS SF Bay Area: Only a week after announcing that he altered the DNA of embryos for seven couples, He Jiankui is now missing. He was last seen at a conference in Hong Kong. Elizabeth Cook reports, and speaks with local expert Marcy Darnovsky, Executive Director of the Center for Genetics and Society. (12-3-2018)
On CGTN America, Marcy Darnovsky, PhD, the executive director of the Center for Genetics and Society, discusses the ethics of human genetic modification.
While embryo selection and gene editing technologies may offer great hope to couples looking to prevent hereditary disease or improve fertility. The debate over these technologies has reignited concerns that we are closer to slipping down the slope to designer babies than ever before. Are these fears warranted…or overblown?