Synthetic Biology

Synthetic biology is an umbrella term that refers to powerful techniques for re-engineering the fundamental molecular structures of life, including genes, genomes, cells, and proteins. Some of the techniques being developed under this rubric enable the modification of existing bacteria to produce useful substances or perform new functions and the creation of novel artificial organisms, so far for research purposes. Synthetic biologists foresee a host of applications, including new methods for producing drugs, biofuels, and vaccines; diagnosing, preventing, and treating disease; and — far more controversially and far-off — synthesizing modified human genes to produce specified traits in future children and generations. Such eugenic visions raise concerns about social justice, human rights, and equality.

Environmentalists and populations near actual or proposed uses of synthetic biology products have voiced concerns about ecological and biosecurity risks. These are especially acute when synthetic biology techniques are combined with “gene drives,” which can enable the rapid spread of modified organisms through the natural population. At present, no comprehensive framework for assessment, oversight, and regulation of synthetic biology exists nationally or internationally.


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Tuesday morning, more than 200 biologists, businesspeople, and ethicists will converge on the New York Genome Center in New York City to jump-start what they hope will be biology’s next blockbuster: Genome Project-write (GP-write), a still-unfunded sequel to the Human...

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Josiah Zayner is the kind of citizen scientist whom journalists like to write about. He left his job as a NASA biologist to start his own company, the Odin, to sell DIY bio products, like a kit for beginners to...

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Is that something we’re comfortable with?

Sure, the U.S. military has deployed the power of biology and nature before. For...

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The debate over a fish shows that scientists can be too quick to dismiss the public’s concerns.

“Keep Frankenfish off...