Human Genetic Modification
Human genetic modification (or “gene editing”) can be used in two very different ways. Somatic genome editing changes the genes in a patient’s cells to treat a medical condition. A few gene therapies are approaching clinical use but remain extraordinarily expensive.
By contrast, heritable genome editing would change genes in eggs, sperm, or early embryos to try to control the traits of a future child. Such alterations would affect every cell of the resulting person and all subsequent generations.
For safety, ethical, and social reasons, heritable genome editing is widely considered unacceptable. It is prohibited in 70 countries and by a binding international treaty. Nevertheless, in 2018 one scientist announced the birth of twins whose embryos he had edited. This reckless experiment intensified debate between advocates of heritable genome editing and those concerned it could exacerbate inequality and lead to a new, market-based eugenics.
Genome editing is a way of making changes to specific parts of a genome. Scientists have been able to alter DNA...
Public and policy conversations about heritable human genome editing often leave the impression that rules governing it are few and...
This debate looks at the long-term challenges and opportunities CRISPR presents, looking closely at two particular consequences: the implications of gene editing on global inequality, and its risk to evolution. The three speakers are: Katie Hasson, policy advocate; Jamie Metzl, futurist and geopolitical expert and author; and Julian Savulescu, philosopher, bioethicist, and author.
Bill McKibben and john a. powell came discuss the “Climate Crisis, Designer Babies, and Our Common Future.” The event was moderated by Osagie K. Obasogie, Professor of Bioethics at UC Berkeley.
George Estreich discusses his most recent book Fables and Futures, inspired by his daughter Laura. Estreich goes beyond the personal to describe the ways that genetic technologies affect society and the stories the promoters of such technologies tell about them. The event took place on May 1, 2019 at the San Francisco Public Library.