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Pregnant woman holding her stomach

Doctors in Newcastle have been granted permission to create Britain’s first “three-person babies” for two women who are at risk of passing on devastating and incurable genetic diseases to their children.

The green light from the fertility regulator means that doctors at the Newcastle Fertility Centre will now attempt to make healthy embryos for the women by merging fertilised eggs created through standard IVF with DNA from female donors. 

The Human Fertilisation and Embryology Authority (HFEA) confirmed on Thursday that it had approved the procedures which will now be overseen by Mary Herbert, professor of reproductive biology, and her team at the Newcastle clinic.

The women will be the first in Britain to have so-called mitochondrial donation therapy, a radical IVF procedure that was made legal by parliamentary vote in 2015. The Newcastle centre was granted a licence to perform the treatment, also known as mitochondrial replacement therapy, in March last year.

While doctors at Newcastle Fertility Centre said they could not to talk about the cases, citing patient confidentiality, minutes from the HFEA’s approval committee reveal that the...