Taking responsibility: Asilomar and its legacy
By J. Benjamin Hurlbut,
Science
| 01. 30. 2025
In February 1975, leading molecular biologists gathered at the Asilomar conference center on the California coast to evaluate risks of the emerging technology of recombinant DNA and to establish guidelines to govern research. The meeting is remembered as a defining moment in the making of molecular biology. Yet its legacy lies not in specific rules it developed but in the approach to scientific self-regulation that it crystallized. Five decades later, this near-mythic “meeting that changed the world” is held up as a precedent to celebrate and a model to emulate: Scientists take responsibility for governing themselves, solidifying public trust while securing future benefits of technology for society. But although this may elicit public acquiescence and secure scientific autonomy in the short run, ultimately it has engendered reactive distrust. The 50th anniversary affords a moment for taking stock of Asilomar’s legacy and its implications for science and democracy. Its lessons are difficult.
The Asilomar meeting is held up as an exemplar of how scientists can navigate between the Scylla of technological risk and the Charybdis of public reaction and overregulation (...
Related Articles
Gray wolf by Jessica Eirich via Unsplash
“I’m not a scarcity guy, I’m an abundance guy”
– Colossal co-founder and CEO Ben Lamm, The New Yorker, 4/14/25
Even the most casual consumers of news will have seen the run of recent headlines featuring the company Colossal Biosciences. On March 4, they announced with great fanfare the world’s first-ever woolly mice, as a first step toward creating a woolly mammoth. Then they topped that on April 7 by unveiling one...
By Katrina Northrop, The Washington Post | 04.06.2025
photo via Wikimedia Commons licensed under CC by 3.0
China's most infamous scientist is attempting a comeback. He Jiankui, who went to jail for three years after claiming he had created the world's first genetically altered babies, says he remains...
By Kevin Davies, Genetic Engineering & Biotechnology News | 03.27.2025
Around 2018–19, there was not a bigger science and ethical story than the debate over heritable human genome editing (HHGE) and the scandal over the “CRISPR babies.” The scientist, He Jiankui, who attempted to engineer the germline of human embryos...
By Megan Molteni, Stat | 03.28.2025
WASHINGTON — Keith Joung knows better than a lot of people what, exactly, it might require to prove to regulators and patients that CRISPR could be safely used to alter the genome of a human embryo. If, of course, society...