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Close up photo of a yellow winged moth against a white background.

A HALF-INCH-LONG MOTH that devours kale, broccoli, and Brussels sprouts may not inspire the same fear as a Zika-carrying mosquito, but the two insects have something in common. Both are being genetically tweaked by UK-based biotech firm Oxitec. Last year, the company made news when it proposed a Florida-based trial of a self-destructive mosquito—designed to stop the spread of Zika virus in native Aedes aegypti mosquitoes.

Now, Oxitec wants to test a genetically modified version of the male diamondback moth to mate with—and eventually destroy—a pest that damages $5 billion worth of cruciferous crops every year worldwide. Like the mosquito, the moth passed laboratory and greenhouse trials and now must pass approval in a open field test. But while the mosquito had to wind its way through the FDA, Oxitec’s moth faces a different set of regulatory hurdles at the USDA. Officials at that agency are currently reviewing whether to allow Cornell University and Oxitec to release tens of thousands of GM moths into a 10-acre site in New York.

For decades, agricultural researchers have battled insect pests that are growing...