Forensic database challenged over ethics of DNA holdings
By Quirin Schiermeier,
Nature
| 06. 15. 2021
Geneticists say a global Y-chromosome database holds profiles from men who are unlikely to have given free informed consent.
In May 1999, a disturbing crime shocked the inhabitants of Kollum, a small village in the Netherlands. A local 16-year-old girl was found raped and murdered in a field nearby, and some people said that Iraqi or Afghan residents at an asylum seekers’ centre in the village could be to blame. Tensions rose: a fight broke out at a planning meeting about the centre. With the case unsolved, the public prosecutor turned to a newly launched research database containing Y-chromosome profiles from men across the world. When forensic scientists compared DNA from semen collected at the crime scene with profiles stored in this Y-chromosome Haplotype Reference Database (YHRD) and elsewhere, they found that the murderer was very probably of northwestern European descent, showing that the villagers’ assumptions were unfounded. The discovery helped to calm social tensions — although the case was not solved for many years until, with the aid of more DNA work, a local farmer was found guilty.
The YHRD, which was first released online in 2000, is now widely used across the world to help solve sex...
Related Articles
By Gaia Ghirardi, Arno Van Hootegem & K. Paige Harden , Nature Human Behaviour | 09.21.2026
Embryo screening for behavioural traits is no longer speculative. If you want to become a parent in the USA today, you can pay to use pre-implantation polygenic testing (PGT-P) of in vitro fertilization (IVF)-created embryos. PGT-P promises to optimize offspring...
Artificial Intelligence (AI) has been a major focus of news recently, as it should have been, under the appropriately ridiculous name of Hugging Face, “a leading collaboration platform and community hub for machine learning, artificial intelligence, and data science.” In July, Hugging Face was hacked. The platform itself responded:
Earlier this week, we detected and responded to an intrusion into part of our production infrastructure. This one was different from anything we had handled before in one important way...
By Ryan Cross, Endpoints News | 09.02.2026
The deaths of two children who received CRISPR therapies in China have rattled scientists who work on similar genetic medicines in the US, adding new fuel to a yearslong debate about the danger of the gene therapy field’s most-used delivery...
By Maia Hibbett, Wired | 09.09.2026
THE INSTAGRAM POST, precision-guided by sex and age, had zeroed in on its target. Yuchen Tu is a conservatory-trained viola player from Chongqing, China, a lover of science fiction, and an aspiring member of the US Army Reserve Officer Training...