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Seven candles are lit in a darkened room.

Chrissy Teigen is nothing if not candid—a quality that the model turned chef and television host is both adored and often berated for. Which is why it comes as no surprise that, in a newly published interview online, she openly discussed that she and her husband, John Legend, are attempting to have a second child through in vitro fertilization.

Following the birth of her daughter, Luna, also conceived by IVF, the process will use one of Teigen’s frozen embryos, the last remaining from the batch of three that she, Legend, and her doctor hand-selected for the ultimate health of the baby and success of her pregnancy. On the celebrity scale, Teigen has been unprecedentedly honest about the struggles of motherhood—from conception to postpartum depression, becoming an unofficial public advocate for IVF, as well as for the right to choose the sex of her first baby. “Not only am I having a girl, but I picked the girl from her little embryo,” she said in an interview before Luna was born, setting off a Twitter debate among critics...