Why you shouldn’t know too much about your own genes
By Carolyn Johnson,
Washington Post
| 09. 11. 2015
Untitled Document
This summer, a panel of genetics experts did something surprising: they put out a list of genetic tests people should not get.
In the age of precision medicine, the genome is our oyster. There are cancer wonder drugs that pinpoint the errant genes that drive tumors. There are longstanding medical mysteries finally being unraveled by DNA sequencing. There is tremendous excitement over the coming age of treatments tailored to you. And there is also this: a very long list of genes for which the best medical understanding of what they mean for our health is essentially a shrug.
The poster child for the uncertainty underlying much of the information in this brave new world is a gene called MTHFR. It produces an important enzyme, but many medical geneticists simply sigh when they hear the gene's clumsy acronym name.
This gene has made its way on to the do-not-test list more than once, because in almost no cases do the tests have any medical utility. Meanwhile, alternative medicine practitioners and Web sites have stepped up their claims that many people --...
Related Articles
By Josie Ensor, The Times | 12.09.2025
A fertility start-up that promises to screen embryos to give would-be parents their “best baby” has come under fire for a “misuse of science”.
Nucleus Genomics describes its mission as “IVF for genetic optimisation”, offering advanced embryo testing that allows...
By Hannah Devlin, The Guardian | 12.06.2025
Couples undergoing IVF in the UK are exploiting an apparent legal loophole to rank their embryos based on genetic predictions of IQ, height and health, the Guardian has learned.
The controversial screening technique, which scores embryos based on their DNA...
By Frankie Fattorini, Pharmaceutical Technology | 12.02.2025
Próspera, a charter city on Roatán island in Honduras, hosts two biotechs working to combat ageing through gene therapy, as the organisation behind the city advertises its “flexible” regulatory jurisdiction to attract more developers.
In 2021, Minicircle set up a...
By Vardit Ravitsky, The Hastings Center | 12.04.2025
Embryo testing is advancing fast—but how far is too far? How and where do we draw the line between preventing disease and selecting for “desirable” traits? What are the ethical implications for parents, children, clinicians, and society at large? These...