Why You Should Be Careful About 23andMe’s Health Test
By The Editorial Board,
The New York Times
| 02. 01. 2019
Last month, the DNA-testing company 23andMe secured Food and Drug Administration approval for a new screening for gene-based health risks. Along with celiac disease, Alzheimer’s, Parkinson’s, breast cancer and several other medical conditions, the company can now screen clients for two mutations that have been linked to colorectal cancer.
But “F.D.A.-approved” does not necessarily mean “clinically useful.” 23andMe relies on much simpler technology than tests that you’d get at your doctor’s office. As a result, the company’s tests cannot tell you much about your actual risk of developing the diseases in question.
Here’s how those tests work — and why you should interpret them with caution.
They read your gene.
You can think of your genes as long text documents. The words are your genetic code. Genetic mutations are like typos — imperfections that scientists can spot with some scrutiny.
They compare your gene against a reference gene to find problems.
DNA tests are scientists’ way of proofreading your genes — which they accomplish by comparing them against a gene that’s considered healthy.
23andMe’s test reviews a handful of locations
...
Related Articles
Paula Amato & Shoukhrat Mitalipov
[OHSU News/Christine Torres Hicks]
On September 30th, a team of 21 scientists from Oregon Health & Science University (OHSU) published a significant paper in Nature Communications, with a scientifically accurate but, to many, somewhat abstruse headline:
Induction of experimental cell division to generate cells with reduced chromosome ploidy
The lead authors were Shoukhrat Mitalipov, recently described here as “a push-the-envelope biologist,” and his long-term colleague Paula Amato. (Recall that in July the pair had co-published with...
By Pam Belluck, The New York Times | 10.17.2025
Before dawn on a March morning, Doug Whitney walked into a medical center 2,000 miles from home, about to transform from a mild-mannered, bespectacled retiree into a superhuman research subject.
First, a doctor inserted a needle into his back to...
By Elizabeth Dwoskin and Zoeann Murphy, The Washington Post | 10.01.2025
MEXICO CITY — When she walked into an IVF clinic in June, Alin Quintana knew it would be the last time she would try to conceive a child. She had prepared herself spiritually and mentally for the visit: She had traveled to a nearby...
By Rob Stein, NPR | 09.30.2025
Scientists have created human eggs containing genes from adult skin cells, a step that someday could help women who are infertile or gay couples have babies with their own genes but would also raise difficult ethical, social and legal issues...
