'Three-Person IVF' Technique Moves Closer
By BBC,
BBC News
| 01. 19. 2012
It replaces defective genetic material in the egg in order to eliminate rare mitochondrial diseases.
After the consultation into "three-person IVF", ministers will decide whether to allow it in patients.
A £5.8m centre at Newcastle University, funded by the Wellcome Trust, will investigate the technique's safety.
Inherited defects
Mitochondria can be found within almost every human cell, and provide the energy they need to function.
Like the nucleus of the cell, they contain DNA, although in tiny quantities.
Approximately 1 in 5,000 babies is born with inherited defects in their mitochondrial DNA, the effects of which can be very severe, or even fatal, depending on which cells are affected.
Scientists believe they have found a way to substitute the defective mitochondria and hopefully prevent the child from developing a disease.
They take two eggs, one from the mother and another from a donor.
The nucleus of the donor egg is removed, leaving the rest of the egg contents, including the mitochondria, and is replaced with the nucleus from the mother's egg.
The resulting embryo has properly functioning mitochondria from the...
Related Articles
By Jason Liebowitz, The New Yorker | 03.06.2026
When Talaya Reid was in high school, in a quiet suburb of Philadelphia, she developed fatigue so severe that she spent afternoons napping instead of going out with friends. She was lethargic at school and her grades suffered, but after...
By Émile P. Torres, Truthdig | 02.26.2026
It’s well known that Jeffrey Epstein was a super-wealthy pedophile with an extraordinary network of powerful friends: tech billionaires, politicians and academics. But few people know that he was also a transhumanist — someone who believes that we should...
By Scott Solomon, The MIT Press Reader | 02.12.2026
Chris Mason is a man in a hurry.
“Sometimes walking from the subway to the lab takes too long, so I’ll start running,” he told me over breakfast at a bistro near his home in Brooklyn on a crisp...
By Zachary Brennan, Endpoints News | 02.23.2026
The FDA is spelling out the details of a new pathway to help speed personalized cell and gene therapies to market for rare diseases.
Monday’s long-awaited draft guidance outlines the agency’s “plausible mechanism” framework, a pathway FDA Commissioner Marty Makary...