Substituting genetic ancestry for race in research? Not so fast
By Anna C. F. Lewis,
STAT
| 05. 02. 2022
Race, widely used as a variable across biomedical research and medicine, is an appropriate proxy for racism — but not for anything biological. Proposals to use genetic ancestry instead of race are at risk of perpetuating the same problems.
Dozens of algorithms widely used in clinical care contain an adjustment factor for a patient’s race. When estimating kidney function, for example, different results are returned depending on whether the patient’s race is entered as “Black” or “non-Black,” though at least for kidney function the use of race is being challenged. Some medications have been approved only for those of certain self-identified racial groups. Meanwhile in research, the race of participants is routinely considered at almost every step of the research process — from recruitment to analysis to the interpretation of findings.
Race-based health disparities have reinvigorated the debate about whether these uses of race are appropriate, and their potential connection to racism.
To be sure, race is an important variable to track in order to understand the social drivers of health, including the impact of racism. But it...
Related Articles
GeneWatch UK has prepared a briefing on the genetic modification of nature for the International Union for Conservation of Nature (IUCN) Congress in October 2025
The upcoming Congress claims to be “where the world comes together to set priorities and drive conservation and sustainable development action.” A major concern for those on the outside is that the Congress may advance plans to develop and encourage the use of synthetic biology in nature conservation. This could at first glance sound like...
By Aaron Ginn, The Washington Post | 09.12.2025
Earlier this year, I had dinner in D.C. with Jensen Huang, the president and chief executive of Nvidia. At one point, he said something that struck me: “Why is everyone here so negative?”
He wasn’t referring to the economy...
By Roni Caryn Rabin, The New York Times | 08.25.2025
Scientists have dreamed for centuries about using animal organs to treat ailing humans. In recent years, those efforts have begun to bear fruit: Researchers have begun transplanting the hearts and kidneys of genetically modified pigs into patients, with varying degrees...
The Center for Genetics and Society is delighted to recommend the current edition of GMWatch Review – Number 589. UK-based GMWatch, a long-standing ally, was founded in 1998 by Jonathan Matthews as an independent organization seeking to counter the enormous corporate political power and propaganda of the GMO industry and its supporters. Matthews and Claire Robinson are its directors and managing editors.
CGS works to ensure that social justice, equity, human rights, and democratic governance are front...