'Smart Genes' Prove Elusive
By Ewen Callaway,
Nature
| 09. 08. 2014
Scientists looking for the genes underlying intelligence are in for a slog. One of the largest, most rigorous genetic studies of human cognition1 has turned up inconclusive findings, and experts concede that they will probably need to scour the genomes of more than 1 million people to confidently identify even a small genetic influence on intelligence and other behavioural traits.
Studies of twins have repeatedly confirmed a genetic basis for intelligence, personality and other aspects of behaviour. But efforts to link IQ to specific variations in DNA have led to a slew of irreproducible results. Critics have alleged that some of these studies' methods were marred by wishful thinking and shoddy statistics. A sobering editorial in the January 2012 issue of Behavior Genetics2 declared that “it now seems likely that many of the published findings of the last decade are wrong or misleading and have not contributed to real advances in knowledge”.
In 2011, an international collaboration of researchers launched an effort to bring more rigour to studies of how genes contribute to behaviour. The group, called the...
Related Articles
By Meagan Parrish, PharmaVoice | 10.10.2025
When CEO Ben Lamm steps into the spotlight, it’s usually to talk about his efforts bringing extinct animals back to life. Once a far-flung idea, Lamm and the company he heads, Colossal Biosciences, have proven they can pull it off...
By Jessica Mouzo, El País | 10.03.2025
DNA is the molecule of life: this double-helix structure, present in every cell in the body and organized into fragments called genes, stores the instructions for making organisms function. It is a highly precise biological machine, but sometimes it breaks...
By Katherine Bourzac, Nature | 09.25.2025
A judge in New York rejected a request on 23 September to disqualify the use of cutting-edge DNA sequencing as evidence in a case against an alleged serial killer. The ruling paves the way for a type of DNA analysis...
By Claire Robinson, GMWatch | 09.29.2025
According to an article on BBC News, the Quadram Institute in Norwich is recruiting 76 people with low vitamin D to take part in the ViTaL-D Study, where some participants will eat soup containing tomatoes that have been genetically...