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Robert G. Edwards's breakthrough development of in vitro fertilization, which led to the birth of the first "test-tube baby," Louise Brown, in 1978, gave humanity the power to do what previously was considered the province of God: create and manipulate human life.

In the ensuing decades, the pioneering techniques that won the British biologist a Nobel Prize on Monday have played a part in controversial scientific advances such as cloning and the creation of human embryonic stem cells while redefining fundamental social roles such as what it means to be a parent or a family.

"The impact on society has been profound," said Lori B. Andrews of the Chicago-Kent College of Law, who studies reproductive technologies. "The creation of a child outside the body for the first time has had scientific and personal implications far, far beyond the 4 million children who have been born through in vitro fertilization."

IVF has been crucial for human embryonic stem cell research because the cells are obtained from embryos left over at infertility clinics. At the same time, the techniques helped lay the...