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Microscope image of H1N1 virus

New genetic tools are making it easier and cheaper to engineer viruses and bacteria, and a report commissioned by the Department of Defense has now ranked the top threats posed by the rapidly advancing field of "synthetic biology."

One of the biggest concerns is the ability to recreate known viruses from scratch in the lab. That means a lab could make a deadly virus that is normally kept under lock and key, such as smallpox.

"Right now, recreating pretty much any virus can be done relatively easily. It requires a certain amount of expertise and resources and knowledge," says Michael Imperiale, a microbiologist at the University of Michigan who chaired the committee convened by the National Academies of Sciences, Engineering, and Medicine to assess the state of synthetic biology and offer advice to defense officials.

As an example of what's possible, Imperiale pointed to the recent and controversial creation of horsepox, a cousin of smallpox, in a Canadian laboratory. "These things can now be done," he said.

Another top danger listed in the report, which was released Tuesday...