The next 20 years of human genomics must be more equitable and more open
By Nature Staff,
| 02. 10. 2021
The first drafts of the human genome, published in Nature and Science 20 years ago, flung open the doors for what some predicted would be ‘biology’s century’. In just one-fifth of the century, the corpus of information has grown from two gappy and error-filled genome sequences to a full account of the genetic variation of hundreds of thousands of individuals around the world, and an increasing number of tools to study it. This special issue of Nature examines how far the human genome sequence has taken us, and how far we have to go. But some aspects of the research ecosystem around the human genome have hardly changed, and that remains a concern.
Many of the ethical, legal and social implications of genome research — including questions of privacy, informed consent and equitable representation of researchers and participants — remain unresolved. Moreover, free and open access to genome data remains unevenly implemented. Just this week, researchers pointed out the problems caused by lack of accessibility to coronavirus genomes in the middle of a pandemic. Researchers, funders and journals will... see more
By Ian Sample and Hannah Devlin, The Guardian | 03.06.2023
The next generation of advanced genetic therapies raises profound medical and ethical issues that must be thrashed out to ensure the game-changing technology benefits patients and society, a group of world-leading experts has warned.
Medicines based on powerful gene editing...
By Letlhokwa George Mpedi, Daily Maverick | 03.15.2023
In his 2021 novel Klara and the Sun, Kazuo Ishiguro painted a disturbing picture of a world where gene editing has become commonplace and carefully outlined the detrimental impact this has on family dynamics, society and the economy...
By Editorial, The Lancet | 03.18.2023
In 2018, during the Second International Summit on Human Genome Editing in Hong Kong, Jiankui He shocked the world by announcing the birth of two children whose genomes he had edited using CRISPR technology. Following widespread condemnation and a criminal...
By Rob Stein, NPR | 03.16.2023
Victoria Gray was wandering through the British Museum in London last week when she spotted a small wooden cross hanging on the wall.
"It's nice seeing all the old artifacts, especially the cross," Gray said. "Religion is something that I...