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Contents of DNA spit kit, revealing a bio specimen bag and a tube container

A year and a half ago, few health insurers would cover a noninvasive prenatal test — which draws blood from a pregnant woman to analyze fetal DNA — unless the pregnancy was considered high-risk, which usually meant the woman was over 35.

The test, which screens for chromosomal abnormalities linked to genetic disorders like Down syndrome, seemed less essential for women with average- or low-risk pregnancies.

Today, at least 30 major U.S. insurers — including Anthem, Cigna and more than a dozen Blue Cross Blue Shield affiliates nationwide — cover the test for average-risk single-gestation pregnancies, expanding access to millions more people.

The turnaround is part of a broader move by insurers to pay for genetic tests and screenings. The technology is advancing quickly, and the cost of many types of tests is plummeting. Not all tests are covered. But increasingly, insurers are willing to cover screenings for genetic mutations linked to breast, colon and prostate cancer.

The trend has sparked concerns about the access insurers could have to the sensitive information such tests reveal.

“We are seeing more insurance...