Embryos donated to science blow the whistle on CRISPR
By Alison Motluk,
HeyReprotech Newsletter
| 06. 23. 2020
The controversial gene-editing technique mis-snips again. And thanks to embryos donated to science, we know about it.
Many people, finding themselves at the end of their reproductive journey, decide to donate their extra embryos "to science." We don't hear all that much about what becomes of these embryos — what scientific advancements they enabled, what policies they influenced, what practices they helped to curtail.
Here is one such story.
Twenty-five embryos were volunteered into a study using CRISPR, a controversial gene-editing technique. (For a bit of background on the science and politics of CRISPR, see this round-up.) All the couples who donated their embryos gave informed consent. They were told about the research project, were given an opportunity to receive counselling about their decision, and agreed that any results from their contribution could be published in scientific journals. No money changed hands for the embryos.
Some of the findings generated by studying these embryos ended up in one of the world's most prestigious scientific journals, Nature, in this study about the role of a particular gene (POU5F1) in early embryological development.
But those embryos went on to play a role in a second...
Related Articles
By Laura DeFrancesco, Nature Biotechnology | 03.17.2026
The first gene editors designed to fix genetic lesions in mutation-agnostic ways are poised to enter the clinic. Tessera Therapeutics and Alltrna, two Flagship Pioneering-funded companies, are gearing up to test novel genetic medicines in humans. Tessera received regulatory clearance...
By Darren Incorvaia, Fierce Biotech | 03.11.2026
A new method for safely inserting large chunks of DNA into genomes has now measured up in mice, potentially paving the way for the next generation of gene editing medicines.
The approach, which is described in a Nature paper...
By Jason Liebowitz, The New Yorker | 03.06.2026
When Talaya Reid was in high school, in a quiet suburb of Philadelphia, she developed fatigue so severe that she spent afternoons napping instead of going out with friends. She was lethargic at school and her grades suffered, but after...
By Scott Solomon, The MIT Press Reader | 02.12.2026
Chris Mason is a man in a hurry.
“Sometimes walking from the subway to the lab takes too long, so I’ll start running,” he told me over breakfast at a bistro near his home in Brooklyn on a crisp...