DNA tests grow more vital in hereditary breast cancer treatments. They also raise unanswerable questions.
By Sarah Elizabeth Richards,
Washington Post
| 03. 15. 2020
When Lisa DeAngelico found out she had Stage 4 breast cancer two years ago at age 47, she says one of the hardest parts about her diagnosis was telling her mother. That’s because her mother had already lost her sister and niece to the disease. They had hoped DeAngelico would be spared from the family curse.
So when DeAngelico’s doctor asked her whether she wanted to undergo DNA testing to better understand her family genetics, she agreed to offer a blood sample and meet with a genetic counselor.
“I hoped that if it did tell me I had a gene, I could tell others in my family that they should get tested early,” says DeAngelico, a hospital administrative coordinator in East Boston.
Surgeons say all breast cancer patients should be offered genetic testing
Yet the results revealed more than a family connection. When her doctor learned that DeAngelico had a mutation in the BRCA2 gene, he explained she also had a risk of ovarian cancer and advised her to have her ovaries and fallopian tubes removed to prevent the cancer...
Related Articles
By Jenny Lange, BioNews | 12.01.2025
A UK toddler with a rare genetic condition was the first person to receive a new gene therapy that appears to halt disease progression.
Oliver, now three years old, has Hunter syndrome, an inherited genetic disorder that leads to physical...
By Rachel Hall, The Guardian | 11.20.2025
Couples are needlessly going through IVF because male infertility is under-researched, with the NHS too often failing to diagnose treatable causes, leading experts have said.
Poor understanding among GPs and a lack of specialists and NHS testing means male infertility...
By Pam Belluck and Carl Zimmer, The New York Times | 11.19.2025
Gene-editing therapies offer great hope for treating rare diseases, but they face big hurdles: the tremendous time and resources involved in devising a treatment that might only apply to a small number of patients.
A study published on Wednesday...
By Aisha Down, The Guardian | 11.10.2025
It has been an excellent year for neurotech, if you ignore the people funding it. In August, a tiny brain implant successfully decoded the inner speech of paralysis patients. In October, an eye implant restored sight to patients who had...