A Decade Later, a Patient Finds Out Her Genetic Test Was Wrong
By Sarah Zhang,
The Atlantic
| 05. 11. 2017
Should scientists give results to participants in research studies if they haven’t been validated in a clinical lab?
SALT LAKE CITY—In the mid-2000s, when Vicki Rieke’s mom was being treated for her second bout of colon cancer in a hospital out of state, doctors suggested it was time to get tested. Colon cancer can be genetic, but it is also one of the more preventable cancers. A genetic test could give Vicki and her siblings life-saving information.
As it turns out, her mom, Dianne King, did have a mutation for Lynch syndrome. The condition predisposes people to a whole host of cancers. (She passed away last month after her sixth cancer.) Her children had a 50/50 percent chance of inheriting that Lynch syndrome mutation. So when the test requested by her mom’s doctors came back positive for Rieke, too, that news didn’t shock her. “It was kind of just not surprising with my mom’s history,” she said.
The shocker came more than 10 years later: Rieke, who is now 46, got retested at a new lab in Utah, and it...
Related Articles
By Tomoko Otake, The Japan Times | 04.09.2024
A decade ago, researcher Haruko Obokata caused a sensation when she published two papers in the journal Nature, in which she claimed that she had discovered a way to create stem cells easily using the so-called STAP method.
With STAP...
By Yelena Biberman and Jonathan D. Moreno, Bioethics Forum | 04.16.2024
A quiet biological revolution in warfare is underway. The genome is emerging as a new domain of conflict. The level of destruction that only nuclear weapons could previously achieve is fast becoming as accessible as a cyberattack.
Now for the...
CGS is excited to announce the launch of a new anti-eugenics initiative that has been years in the making. Legacies of Eugenics in Science, Medicine, and Technology kicks off with a monthly essay series published at the Los Angeles Review of Books that will expose and contest the reemergence of eugenic ideas in contemporary health sciences, human biotechnology, public health, and medicine. Community and campus-based events featuring the authors are also being planned. The project is a collaboration among CGS...
By Tristan Manalac, BioSpace | 04.02.2024
Verve Therapeutics has suspended enrollment in the Phase Ib Heart-1 study evaluating its lead gene editing program VERVE-101 following a serious adverse event, the company announced Tuesday.
A patient, who received a 0.45-mg/kg dose of VERVE-101, developed a grade 3...