The beautiful science of embryology
By Kate Womersley,
Prospect
| 03. 03. 2021
It’s a familiar story: the virile sperm fights its path through the hostile uterus to the passive female egg. After fertilisation, the resulting ball of cells is “totipotent,” with each unit equally capable of becoming any cell type in the placenta or foetus. Magdalena Zernicka-Goetz, an embryologist from the University of Cambridge, affronted her field by claiming this was wrong: not just the sexist metaphors, but also the assumption that the first human cells are identical. Her experiments showed that cells lean towards a particular fate, and that an embryo’s symmetry is broken from its earliest moments.
Together with science journalist Roger Highfield, Zernicka-Goetz leads us through the intricacies of modern embryology and reproductive technology. Her successes include doubling the length of time embryos can survive in the lab, building simulation mouse embryos out of stem cells and using fluorescent labels to make “embryo art.” “We are entering a new era,” she writes, “one where we can manipulate the cellular units of life as skilfully as a potter works clay.” While gene editing and designer babies raise understandable alarm, artistry...
Related Articles
By Mary Annette Pember, ICT News [cites CGS' Katie Hasson] | 04.18.2025
The sight of a room full of human cadavers can be off-putting for some, but not for Haley Omeasoo.
In fact, Omeasoo’s comfort level and lack of squeamishness convinced her to pursue studies in forensics and how DNA can be...
Gray wolf by Jessica Eirich via Unsplash
“I’m not a scarcity guy, I’m an abundance guy”
– Colossal co-founder and CEO Ben Lamm, The New Yorker, 4/14/25
Even the most casual consumers of news will have seen the run of recent headlines featuring the company Colossal Biosciences. On March 4, they announced with great fanfare the world’s first-ever woolly mice, as a first step toward creating a woolly mammoth. Then they topped that on April 7 by unveiling one...
By Katrina Northrop, The Washington Post | 04.06.2025
photo via Wikimedia Commons licensed under CC by 3.0
China's most infamous scientist is attempting a comeback. He Jiankui, who went to jail for three years after claiming he had created the world's first genetically altered babies, says he remains...
By Anumita Kaur [cites CGS’ Katie Hasson], The Washington Post | 03.25.2025
Genetic information company 23andMe has said that it is headed to bankruptcy court, raising questions for what happens to the DNA shared by millions of people with the company via saliva test kits.
Sunday’s announcement clears the way for a new...