3-Person IVF: Overviews and Background
The following links provide broad overviews of "3-person embryos" - the technology, safety and efficacy, and social and ethical considerations. The five resources vary considerably in tone and content.
- FDA Briefing Document- Oocyte Modification in Assisted Reproduction for the Prevention of Transmission of Mitochondrial Disease or Treatment of Infertility
- The Swedish National Council on Medical Ethics English summary of their report on Mitochondria replacement
- Human Genetics Alert's mitochondria briefing
- Nuffield Council on Bioethics' report on mitochondria replacement
- Human Fertilisation and Embryology Authority (HFEA) materials on mitochondria replacement
The following links to a pdf, which includes a summary of national policies on inheritable genetic modification. It is from a testimony given at the House Foreign Affairs Committee Subcommittee on Terrorism, Nonproliferation and Trade by former executive director of CGS, Richard Hayes, Ph.D.
- Is There an Emerging International Consensus On the Proper Uses Of the New Human Genetic Technologies?
The following two links provide background information on ooplasmic transfer (also called cytoplasmic transfer,) a similar technique to "mitochondrial replacement," attempted for the purpose of treating infertility, that was stopped by the FDA in 2001 due to various problems and concerns.
- Informational page on ooplasmic transfer
- “World's First GM Babies Born”: 12-Year-Old Article Continues to Cause Confusion