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FRIDAY, Sept. 28 (HealthDay News) -- A sophisticated genetic test sometimes used during pregnancy can't always predict if chromosomal abnormalities will cause problems in children, leading some mothers to label the information "toxic knowledge" they wish they hadn't received, a small new study shows.

Researchers from three universities found that expectant mothers receiving bad news about a genetic test called a DNA microarray -- more often used after birth to identify chromosomal problems in children with unexplained delays or defects -- reported mostly negative responses, ranging from feeling blindsided to needing support to digest the information and make critical decisions about their pregnancies.

The women's reactions challenge the notion that knowledge is power, especially when that knowledge pertains to ambiguous information about an unborn baby's health, said study author Barbara Bernhardt, a genetic counselor and clinical professor of medicine at the Hospital of the University of Pennsylvania.

"I think we need to have better information readily available to patients and providers . . . to make the decisions they need to make in a timely manner," Bernhardt said. "We also...