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WASHINGTON - Paul Ryan's record on women's issues and abortion is coming into sharpened focus since Mitt Romney tapped him as his running mate — in particular, the lawmaker's anti-abortion bill that puts him at odds with the eldest son of the Republican presidential hopeful.

Tagg Romney and his wife, Jen, announced the birth of twin boys in May with the help of a surrogate mother and in vitro fertilization — a form of assisted reproductive technology that could be rendered illegal under the Sanctity of Human Life Act, co-sponsored by Ryan.

The bill states that human life begins the moment an egg is fertilized. But in IVF, some embryos are typically destroyed or discarded in the process after being fertilized by sperm outside the body.

Typically, doctors fertilize several eggs; the ones that fail to thrive after being implanted in the womb are discarded. Leftover embryos that are not implanted are often frozen, used for medical research or destroyed.

Many right-to-life groups oppose IVF since it results in the destruction of human embryos.

Women's groups have been zeroing in...