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Their key role in the arcane world of surrogate motherhood has received relatively little scientific examination, but it turns out surrogates are often deeply upset by the process, a new Canadian case study suggests.

Women who get pregnant for others frequently suffer separation anxiety and depression when they have to hand over the newborn to the would-be parents, researchers at a Vancouver fertility clinic report. Some also become angry when their contact with the parents is limited.

The researchers say their findings should serve as a warning for fertility-clinic staff who screen potential “gestational” carriers, women implanted with an embryo fertilized using someone else’s eggs.

“In spite of pre-treatment counselling, we have noted significant emotional issues occurring among some of the carriers,” their report to this week’s Canadian Fertility & Andrology Society conference notes.

“Some have demonstrated significant separation anxiety and depression (when required to give up) the newborn infant to the intended parents and to remove themselves from any contact with the child.”

In other presentations at the conference Thursday, a lawyer who has handled 1,500 surrogacy motherhoods admitted...