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When Richmond was selected as the site for Lawrence Berkeley National Laboratory's huge second campus in January, city officials and community leaders celebrated the "green" jobs it would create, hundreds of them, diversifying an economy dependent on Chevron and its massive oil refinery. But a new coalition called Synbiowatch (www.synbiowatch.org) is questioning how green those jobs really are and raising fears about the new scientific realm on which they rely.

It's called synthetic biology, which combines engineering and computer science with the biological sciences to design new microbes that don't exist in nature — living, self-replicating organisms — taking the field of genetic engineering to another level by allowing scientists to actually write new DNA codes and incubate new life forms.

Proponents tout myriad potential benefits from the approach, from medical treatments (such as developing new anti-malarial drugs or creating new viruses that would attack cancer cells in humans) to the creation of renewable energy sources that might eventually replace fossil fuels, a major focus of the new lab and its main partner, the U.S. Department of Energy's...