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About Inheritable Genetic Modification


The Basic Science

Frequently Asked Questions

Arguments Pro & Con

3-Person IVF

Inheritable genetic modification (IGM, also called germline engineering) means changing the genes passed on to future generations. The genetic changes would be made in eggs, sperm or early embryos; modified genes would appear not only in the person who developed from that gamete or embryo, but also in all succeeding generations. IGM has not been tried in humans. It would be by far the most consequential type of genetic modification as it would open the door to irreversibly altering the human species.

Proposals for inheritable genetic modification in humans combine techniques involving in vitro fertilization (IVF), gene transfer, stem cells and research cloning.



Biopolitical News of 2014by Pete Shanks, Jessica Cussins & Marcy DarnovskyBiopolitical TimesDecember 18th, 2014This is everything important that happened in biopolitics in 2014 (or close to it).
Top Biopolitical Times Posts of 2014by Jessica Cussins & Pete ShanksBiopolitical TimesDecember 18th, 2014In 2014, CGS staffers and contributors posted 107 blogs in Biopolitical Times. These are twelve of our favorites.
Rules for Babies 'From Three People'by James GallagherBBCDecember 17th, 2014With the regulations now finalized, MPs will soon vote on whether to make the UK the only country in the world to legalize a form of human germline modification.
Yesterday's War; Tomorrow's Technology by Nicholas G. Evans and Jonathan D. MorenoJournal of Law and the BiosciencesDecember 15th, 2014What's wrong with the prospect of the US military using genetic screening and germline genetic engineering to select or "enhance" soldiers?
The ‘Science’ of Eugenics: America’s Moral Detourby Marilyn M. SingletonJournal of American Physicians and SurgeonsDecember 15th, 2014Within 100 years, our deep thinkers went from declaring that in our new country “all men are created equal” to espousing the idea that “some men are more equal than others.”
Commercialisation and the Moral Obligation to Create 'Designer' Babiesby John GallowayBioNewsDecember 8th, 2014Julian Savulescu made the case for a new 'eugenics', without ever using the word, at Progress Educational Trust's 2014 annual conference.
Couple Spends $50K to Choose Baby's Sex, Shining Light on Trend[Quotes CGS's Marcy Darnovsky]by Beth GreenfieldYahooDecember 5th, 2014What if a boy wants to write poetry? What if a girl wants to play basketball? Not wear dresses? Announce that she’s transgender?
Who Owns the Biggest Biotech Discovery of the Century?by Antonio RegaladoMIT Technology ReviewDecember 4th, 2014At stake are rights to an invention that may be the most important new genetic engineering technique since the beginning of the biotechnology age in the 1970s: the CRISPR system.
CRISPR Opportunities … For What? And For Whom? by Pete ShanksBiopolitical TimesDecember 4th, 2014Money and deals are flowing into the companies founded on CRISPR technology, which promises to enable the precise editing of genomes.
Deceptive Labeling of a Radical Embryo Construction Techniqueby Stuart A. NewmanThe Huffington PostDecember 1st, 2014The British Parliament appears poised to give the go-ahead to a set of techniques for generating infants which, if implemented, would constitute the first cases of large-scale human genetic engineering.
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