Home Overview Press Room Blog Publications For Students about us
Search

About Inheritable Genetic Modification


The Basic Science

Frequently Asked Questions

Arguments Pro & Con

3-Person IVF

Inheritable genetic modification (IGM, also called germline engineering) means changing the genes passed on to future generations. The genetic changes would be made in eggs, sperm or early embryos; modified genes would appear not only in the person who developed from that gamete or embryo, but also in all succeeding generations. IGM has not been tried in humans. It would be by far the most consequential type of genetic modification as it would open the door to irreversibly altering the human species.

Proposals for inheritable genetic modification in humans combine techniques involving in vitro fertilization (IVF), gene transfer, stem cells and research cloning.



DNA Editing in Mouse Embryos Prevents Disease[Quotes CGS's Marcy Darnovsky]by Sara ReardonNature NewsApril 23rd, 2015“It is a bit of a slippery slope — if you start allowing any editing tool, you open a Pandora’s box of the possibility to edit anything.”
Chinese Gene-Editing Experiment Creeps Out Scientists[Quotes CGS's Marcy Darnovsky]by Maggie FoxNBC NewsApril 23rd, 2015The work raises the specter of eugenics — making designer babies, or trying to "improve" the human race.
Critics Lash Out At Chinese Scientists Who Edited DNA In Human Embryos[Quotes CGS's Marcy Darnovsky]by Rob SteinNPRApril 23rd, 2015For the first time, scientists have edited DNA in human embryos, a highly controversial step long considered off limits.
Editing Human Embryos: So This Happenedby Carl ZimmerNational GeographicApril 22nd, 2015A quick guide to the history behind this research, what the Chinese scientists did, and what it may signify.
Chinese Scientists Genetically Modify Human Embryosby David Cyranoski & Sara ReardonNature NewsApril 22nd, 2015Rumours of germline modification prove true — and look set to reignite an ethical debate.
Public interest group calls for strengthening global policies against human germline modification[Press statement]April 22nd, 2015“No researcher has the moral warrant to flout the globally widespread policy agreement against altering the human germline.”
Panel discussion on the Ethical and Social Policy Considerations of Novel Techniques for Prevention of Maternal Transmission of Mitochondrial DNA Diseases (March/April 2015) [VIDEO][With CGS's Marcy Darnovsky]
Calling for “More than a Moratorium” on Human Germline Modificationby Jessica CussinsBiopolitical TimesApril 9th, 2015A broader array of critical responses and policy suggestions follows recent reports that the gene-editing technique CRISPR has been used to genetically modify human sperm, eggs or embryos.
Genetic Engineering & The Future of Humankindby Jamie MetzlIvy MagazineApril 9th, 2015We’re on the verge of this fundamental transformation, not just of our reproductive processes, but of how we think of ourselves as humans.
DARPA, Synthetic Biology and Human Germline Engineering by Pete ShanksBiopolitical TimesApril 9th, 2015The Defense Advanced Research Projects Agency is committed to synthetic biology as one of its four main project areas, and may be involved in human germline experiments.
Displaying 1-10 of 487  
Next >> 
Last Page » 
« Show Complete List » 


ESPAÑOL | PORTUGUÊS | Русский

home | overview | blog | publications| about us | donate | newsletter | press room | privacy policy

CGS • 1936 University Ave, Suite 350, Berkeley, CA 94704 • • (p) 1.510.665.7760 • (F) 1.510.665.8760