|Three-Parent IVF: What's The Hurry?[Quotes CGS's Marcy Darnovsky], ForbesFebruary 28th, 2015Science shouldn’t be a rush order, especially when the health and well-being of a future generation and its descendants depends on it.|
|Reproduction 3.0, Bioethics BulletinFebruary 26th, 2015When you use a technology in a new way like this, it really challenges our notions of what it means to be a parent and what it means to be a family.|
|Three Parent Babies: Unethical, Unnecessary, Unsafe , BioNewsFebruary 16th, 2015The risks these new experiments hold for the lives and health of human embryos, children and egg donors, and the unprecedented modification of the human germline, together provide a case for not crossing this Rubicon.|
|The Future of Conception, Biopolitical TimesJanuary 8th, 2015Numerous writers took advantage of the ending year to look broadly at just how drastically we are changing the process of baby-making, and what it all means for society.|
|Biopolitical News of 2014, Biopolitical TimesDecember 19th, 2014This is everything important that happened in biopolitics in 2014 (or close to it).|
|Top Biopolitical Times Posts of 2014, Biopolitical TimesDecember 18th, 2014In 2014, CGS staffers and contributors posted 107 blogs in Biopolitical Times. These are twelve of our favorites.|
|Rules for Babies 'From Three People', BBCDecember 17th, 2014With the regulations now finalized, MPs will soon vote on whether to make the UK the only country in the world to legalize a form of human germline modification.|
|Why Worry About Genetically Modified Babies?, GeneWatchNovember 24th, 2014The terms "genetically modified babies" and "designer babies" are attention-getters. But beyond the catchy sound bites, what do they really mean - and are they something we need to worry about?|
|What Good is a Scientific Meeting If You Dismiss the Science?, Biopolitical TimesOctober 29th, 2014The Science and Technology Committee of the UK Parliament held an evidence hearing last week to examine the science and proposed regulation of so-called “mitochondrial donation,” or “3-person IVF,” but huge swaths of evidence were widely dismissed.|
|“Evolution right now is in the marketplace”, Biopolitical TimesSeptember 11th, 2014George Church is as outrageous as ever, while both transhumanist ideas and concerns about increasing inequality are receiving more attention.|
|"3-Person IVF" Debated in UK Parliament, Biopolitical TimesSeptember 3rd, 2014The debate in Britain over combining eggs or embryos to prevent the transmission of mitochondrial disease received a public airing, though no firm conclusion, in the House of Commons on September 1st.|
|Failures and Risks in Biosafety Regulation, Biopolitical TimesJuly 24th, 2014Accidents at CDC and elsewhere point up the difficulties in regulating potentially dangerous releases of genetically modified organisms, which scientists are, quite responsibly, discussing.|
|Three Person IVF Plans 'Progress' in UK, BBCJuly 22nd, 2014"Looking back 15 years from now in the midst of a designer baby marketplace, people will see this as the moment when the crucial ethical line was crossed."|
|"3-Person IVF” Update Reveals How Little We Know, Biopolitical TimesJune 5th, 2014A new report on the safety and efficacy of three-person IVF confirms that it would be dangerous and misguided to allow these techniques into UK fertility clinics anytime soon.|
|Making Babies, The AtlanticMay 21st, 2014Some guesses about how the future may change what’s involved in making a person—from the ease of getting pregnant, to the mechanics of procreation, to our very definition of family.|
|RADIO: Mothers for a Human Future[With CGS's Marcy Darnovsky], VoiceAmericaMay 19th, 2014Enola Aird and Marcy Darnovsky discuss the ways in which human genetic engineering and assisted reproductive technologies are developing.|
|Their Foremothers’ Daughters[Quotes CGS's Marcy Darnovsky], The Jewish WeekMay 7th, 2014Jewish culture tends to appreciate scientific fervor, but a small group of American Jews are sounding a warning about the risks that can come with assisted reproductive technologies.|
|Beyond-DNA Day, Biopolitical TimesApril 25th, 2014With a patent now issued for CRISPR genome-editing technology, and the first gene therapy approved by the FDA, this DNA Day will be remembered not for increased understanding of the human genome, but for increased attempts to change it.|
|Stirring the Simmering “Designer Baby” Pot, ScienceMarch 14th, 2014Good ethics begins with good facts, but the effort by the FDA to get the facts straight is just the beginning of the conversation we must have on the wisdom of new reproductive technologies. |
|Three-Parent Babies and Eugenics, GenotopiaMarch 6th, 2014The “three-parent baby” is most certainly genetic engineering — it just modifies “cassettes” of genes, if you will, rather than tweaking single genes or nucleotides. It is exactly as eugenic as going through conventional IVF and selecting the traits you want in your offspring.|
|Human Longevity, Inc., Biopolitical TimesMarch 6th, 2014Craig Venter's new genomics company may face some stiff competition.|
|FDA Weighs Unknowns of 3-Person Embryo Fertilization[Quotes CGS's Marcy Darnovsky], Associated PressFebruary 26th, 2014Genetic experts cautioned that it could take decades to confirm the safety of an experimental technique, meant to prevent children from inheriting debilitating diseases, that would create babies from the DNA of three people.|
|The New Science Of Three-Parent Babies[With CGS's Marcy Darnovsky], NPR On PointFebruary 26th, 2014Mixing DNA from three people to produce one healthy baby. We’ll look at the controversial world of mitochondrial manipulation therapies to avoid inherited disease.|
|Genetically Modified Babies, The New York TimesFebruary 23rd, 2014An advisory committee of the Food and Drug Administration is set to consider radical biological procedures that, if successful, would produce genetically modified human beings. This is a dangerous step. |
|FDA Asked to Approve Creation of Genetically Modified Children, Huffington PostFebruary 20th, 2014The creation of "three-parent babies" has been touted as a relatively trivial tweaking of the reproductive process to enable women with compromised eggs to become genetic mothers of unaffected children. These claims of high impact health benefits from a low-risk procedure cannot be squared with scientific reality.|
|Rewriting the Human Genome, MIT Technology ReviewFebruary 12th, 2014CRISPR could make gene therapies more broadly applicable, but, according to George Church, some scientists will be tempted to use it to engineer embryos during in vitro fertilization. |
|Questions Relating to 'Mitochondrial Replacement', BioNewsFebruary 10th, 2014The term 'mitochondrial replacement' misrepresents reality while making it difficult for the general public to make an informed decision about the procedures and the grave ethical difficulties they raise for both individuals and the whole of society.|
|IngeniousThe EconomistFebruary 8th, 2014It sounds like science fiction, but gene therapy — introducing copies of healthy genes into people who lack them, to treat disease — is looking as if it may become science fact.|
|First Transgenic Monkeys Born Via “Precision Gene Editing”, Biopolitical TimesFebruary 6th, 2014Chinese scientists announced the birth of the first primates created with a precision gene modification technique, raising both hopes about new insights into human diseases and concerns about new attempts at human inheritable genetic engineering.
|CGS Summary of Public Opinion PollsFebruary 4th, 2014This page offers comparisons of survey results for three technologies: reproductive cloning, research cloning, and inheritable genetic modification.|
|Building the Better Baby, Bioethics.netJanuary 21st, 2014BGI, the Chinese company, is hoping that it will soon be able to offer parents an option like that in GATTACA — choosing the “smartest” embryo.|
|There’s a Gene for That, JacobinJanuary 18th, 2014History is littered with horrifying examples of the misuse of evolutionary theory to justify power and inequality. Welcome to a new age of biological determinism.|
|DNA Dreaming, Biopolitical TimesJanuary 13th, 2014A new documentary looks at the Chinese company that styles itself "the world’s largest genomics organization,” and its hunt for the genetic basis of intelligence. |
|Gene doping: Sport's biggest battle? , BBC NewsJanuary 11th, 2014Gene doping may already be happening, but testing authorities are reluctant to discuss the specifics, and some researchers see ethical issues in withholding treatments.|
|FDA Meeting on Mitochondrial Replacement Rescheduled, Biopolitical TimesJanuary 3rd, 2014The FDA public meeting to discuss “oocyte modification in assisted reproduction” that was postponed due to the government shutdown in October has now been rescheduled for February 25-26.
|Biopolitical News of the Year 2013, Biopolitical TimesDecember 19th, 2013For better and worse, 2013 has been a year in which several related issues familiar to those who follow human biotechnology moved into the wider sphere of public discussion.|
|New Ways to Engineer the Germline, Biopolitical TimesDecember 18th, 2013A look at a number of emerging techniques that could compromise the international consensus against human inheritable genetic modification.
|The Three-Parent Dilemma
, MomsRisingDecember 17th, 2013The United Kingdom is on the verge of permitting scientists to move forward with a procedure that would alter the human germline. Mothers everywhere should be deeply concerned.
|Epigenetics: From Heresy to Fact? , Biopolitical TimesDecember 5th, 2013A just-published paper suggests that learned fears can be inherited through multiple generations and adds fuel to the fire of the controversial debate over transgenerational behavioral epigenetics.
|Crispr Goes Commercial , Biopolitical TimesDecember 5th, 2013A new company, Editas Medicine, has been founded by the scientists who developed Crispr gene-editing technology, with backing from several major venture capital funds.|
|Are Three Parents One Too Many?[Quotes CGS], BloombergNovember 27th, 2013The U.K. may soon approve a regulatory proposal that would allow scientists to create a human embryo using the DNA of three individuals. What’s striking is how the many opponents span the political spectrum.|
|Company Patenting Tech for Designing Babies[With CGS's Marcy Darnovsky], KTVUNovember 20th, 2013Biotechnology may give parents unprecedented choices. Fertility clinics already use pre-implantation genetic diagnosis to select traits for some in-vitro babies, but intentional manipulation might create ethical nightmares.|
|Philanthropy's Original Sin, The New AtlantisNovember 15th, 2013For all of philanthropy's wonderful qualities, it's important to understand that the first American foundations were deeply immersed in eugenics — the effort to promote the reproduction of the “fit” and to suppress the reproduction of the “unfit.”|
|Designing Children, Genomics Law ReportNovember 12th, 2013Some degree of mastery over the genetic future of the human species seems to be a possibility. For whom and for what does this technology exist?|
|Future Past: Disability, Eugenics, & Brave New Worlds, Biopolitical TimesNovember 7th, 2013A public symposium held on November 1 at San Francisco State University provided a rare and important opportunity to engage with the historical and ongoing implications of eugenic ideologies and practices for people with disabilities.
|FDA Meeting on Germline Mitochondrial Replacement Postponed, Biopolitical TimesOctober 22nd, 2013The FDA public meeting to discuss a form of human inheritable genetic modification has been postponed because of the aftermath of the government shutdown; now there is more time to spread the word and get involved.|
|Update: The FDA and the Human Germline, Biopolitical TimesOctober 10th, 2013The FDA's scheduled October 22–23 meeting to discuss germline mitochondrial replacement is attracting attention from the media and elsewhere.|
|The Arlene Bynon Show[With CGS's Marcy Darnovsky], The Arlene Bynon ShowOctober 7th, 2013Marcy Darnovsky discusses 23andMe's recent "designer baby" patent with on a national affairs program broadcast on SiriusXM. |
|3-Person IVFLearn more about controversial research on "3-person IVF": how it works, where the research is taking place, the social and ethical implications, and how you can get involved in the discussion.|
|Scientists Warn Against “Three-Parent IVF” Experiment, Biopolitical TimesSeptember 25th, 2013Three evolutionary biologists enumerate a number of scientific studies and methodological shortcomings that have been overlooked in the debate on mitochondrial replacement. Their study has elicited numerous defensive responses, despite bringing important details to bear.|
|FDA to Hold First Public Hearing on GM Babies[Quotes CGS's Richard Hayes and Jessica Cussins], Activist PostSeptember 16th, 2013Next month, the US Food and Drug Administration will hold a two-day public meeting to discuss genetic modification within the human egg, changes which will be passed on generationally.|
|Designer Babies[With CGS's Marcy Darnovsky], Blog Talk RadioSeptember 12th, 2013This week's Roundtable with Stephanie Robinson takes on science, the field of genetics, and the current dilemma regarding its ethics and limitations.|
|Made With Love, Biopolitical TimesJuly 22nd, 2013The first baby has been born following “next generation genetic sequencing” of IVF embryos. What are the implications?|
|Eight Misconceptions about “Three-Parent Babies”, Biopolitical TimesJuly 9th, 2013Amid the talk about “mitochondria replacement” or “three-parent babies," here are the top misconceptions proliferating about the efficacy, safety, public support, and societal implications.|
|Three Person IVF, Practical EthicsJune 29th, 2013Unfortunately, this debate, like so many others in announcements of developing science and technology related to health in general and genetics in particular, is marred by hype and by urgency.|
|Three Parent Baby[With CGS's Marcy Darnovsky]KPIX HealthWatchJune 27th, 2013Mitochondrial replacement would create "three parent babies," and could be attempted in humans soon, but carries risks to the child and broad societal consequences.|
|Lieber Adoptieren, The EuropeanJune 26th, 2013Die Keimbahntherapie weckt falsche Hoffnungen. Den Nutzen, den sie für eine winzige Minderheit bedeuten könnte, wiege das hohe Risiko keineswegs auf.|
|The Baby Blueprint [VIDEO][With CGS's Marcy Darnovsky]Al Jazeera EnglishApril 22nd, 2013Would you choose your child's genetic potential? Live debate with Marcy Darnovsky, Stuart Newman, Julian Savulescu, and Nita Farahany.|
|GM Babies?, Biopolitical TimesMarch 5th, 2013A debate about genetically engineered babies is hijacked by slick rhetoric.
|Neo Neanderthal[With CGS's Pete Shanks], HuffPost LiveJanuary 25th, 2013A leading geneticist at Harvard Medical School says he can clone a Neanderthal and resurrect the extinct species. What are the ethical issues, risks and benefits?|
|Biotech's 10 Biggest PR Disasters of 2012GMWatchDecember 31st, 20122012 was the year the lights came up on the biotech industry. Its claims, its tactics and its products all came under scrutiny and some of its biggest PR fairytales bit the dust. Here are some prime examples.|
|Brave New Cells?, Project SyndicateDecember 29th, 2012Supporters of mitochondria replacement neglect a crucial factor in the debate: the techniques being developed involve permanent genetic alterations passed on to future generations.|
|Clones and Cloud Atlas, Biopolitical TimesNovember 13th, 2012Of the many characters in Cloud Atlas that explore what it means to be human, the most eloquent is a genetically engineered clone.|
|Of Yeast Genes and Tinker ToysOctober 31st, 2012A recently published paper sounds a serious warning to those who want to tinker around with human genes.
|Genetic Breakthrough at OHSU[With CGS's Marcy Darnovsky], Oregon Public RadioOctober 29th, 2012Researchers in Oregon have created a viable human embryo by combining genetic material from two women's eggs, raising safety and ethical questions. |
|Advocating Human Germline Interventions, Biopolitical TimesOctober 28th, 2012Scientists in Oregon have published a paper that explicitly challenges the legal and procedural system that forbids genetic experiments on future generations, but most reports miss the full implications of the announcement.|
|Ethics Schmethics Says Ethicist, Biopolitical TimesJuly 19th, 2012The approach of the Olympics sparks the usual flood of pro-enhancement articles, notably an interview with Julian Savulescu. |
|Designer Babies in Popular Culture, Biopolitical TimesJune 21st, 2012The Whitest Kids U’Know’s comedic parody of genetic counseling is reminiscent of a similar scene in GATTACA.
|Worrying New Signs of Interest in Re-engineering Humans, Biopolitical TimesFebruary 23rd, 2012Several academics and defense department employees are actively discussing the idea of engineering people, for warfare, to express social values and even to react to climate change.|
|Eric Lander on Scientific Responsibility, Biopolitical TimesJanuary 9th, 2012Geneticist Eric Lander was the only scientist of anything like his level of prominence to publicly oppose the researchers campaigning for the development of "designer baby" technology.|
|New Buzz around Biological Hazards, Biopolical TimesNovember 1st, 2011Recent reports highlight emerging biological engineering risks that might not be all that different from threats of bioterrorism, though the context of development surely differs.
|Lab Fight Raises U.S. Security Issues, New York TimesOctober 22nd, 2011Biosafety expert Paul Rabinow resigned from the UC Berkeley-led Synthetic Biology Engineering Research Center, and asserted that the Center is not doing enough to prevent a biological disaster.|
|Set a bug to kill a bug, Nature NewsAugust 16th, 2011Engineered bacteria that can detect and kill human pathogens could provide a new way to treat antibiotic-resistant bacteria, although researchers say they won't be injected into people any time soon.
|Identical Twins Are Genetically Different, Biopolitical TimesApril 5th, 2011Researchers looking for a genetic basis for schizophrenia report that monozygotic twins, always assumed to be genetically identical, in fact have different DNA.|
|Gene of the Week: Christianity, Biopolitical TimesApril 1st, 2011Gay scientists are reported to have isolate the 'Christian gene' and to have successfully removed it from experimental rats.|
|Return of the GenRich?, Biopolitical TimesOctober 29th, 2009There has been a brief flurry of discussion about future separate species of humans.|
|Monkeys, Mitochondria, and the Human Germline , Bioethics ForumSeptember 18th, 2009The researchers into radically novel techniques display an alarmingly casual attitude toward risks to the potential children born, the difficulties and dangers of obtaining the large numbers of the required women's eggs, and the potentially dire social consequences of human inheritable genetic modification.|
|Michael Sandel on genetics, morality, and a new politics of the common good, Biopolitical TimesSeptember 11th, 2009"It is tempting to think that bioengineering our children and ourselves for success in a competitive society is an exercise of freedom. But changing our nature to fit the world, rather than the other way around, is actually the deepest form of disempowerment."|
|New Genetic Therapy [includes audio], Think Out LoudSeptember 1st, 2009CGS's Marcy Darnovsky and researcher Shoukhrat Mitolipov debate the implications of a new study about mitochondrial DNA for inheritable genetic modification on this call-in radio show.|
|Modified Marmoset in the Media, Biopolitical TimesMay 29th, 2009American media coverage of genetically modified primates was remarkably thin, and few articles mentioned social and ethical implications|
|Public interest group urges caution in response to genetically modified primatesCenter for Genetics and Society calls for scientists, policymakers to reject human inheritable genetic modificationMay 27th, 2009The Center for Genetics and Society today said that the creation of a transgenic marmoset underlines the need for scientists and policy makers to reject human inheritable genetic modification.|
|There's no success like failure ..., Biopolitical TimesFebruary 6th, 2009Another attempt to clone an extinct species has failed, but been widely hailed as a success. Many more have been and are being considered.|
|Appleyard on H+, Biopolitical TimesOctober 22nd, 2008Brian Appleyard weighs in on "risible" transhumanists.|
|Hank Greely on CGS and Human Genetic Modification, Biopolitical TimesSeptember 19th, 2008While Stanford bioethicist Hank Greeley denies being "enthusiastic" about human genetic modification, he's certainly opposed to prohibitions on it or on reproductive cloning.|
|Inequality and Human Genetics[Letter to the editor], The New York TimesSeptember 16th, 2008The genetic modification of our children is a practice that conservatives and liberals alike should be able to agree poses far more risks than benefits, and should be taken off the table as an option.|
|All in the Genes, DemocracyAugust 31st, 2008A letter exchange between CGS's Marcy Dranovsky and bioethicist Hank Greely of Stanford University in the Fall 2008 edition of Democracy: A Journal of Ideas.|
|Happy Birthday!, Biopolitical TimesJuly 25th, 2008Louise Brown's 30th birthday is also the 30th anniversary of the start of the modern assisted reproduction industry.|
|Germline Modification Carries Risk of Major Social Harm
, NatureJune 4th, 2008In this letter to the editor, CGS's Darnovsky points out that when discussing the potential to derive gametes from stem cells, we must be willing to draw lines proscribing socially pernicious applications.|