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Melissa and her husband started trying to have a baby right after they got married. But nothing was happening. So they went to a fertility clinic and tried round after round of everything the doctors had to offer. Nothing worked.

"They basically told me, 'You know, you have no chance of getting pregnant,' " says Melissa, who asked to be identified only by her first name to protect her privacy.

But Melissa, 30, who lives in Ontario, Canada, didn't give up. She switched clinics and kept trying. She got pregnant once, but that ended in a miscarriage.

"You just feel like your body's letting you down. And you don't know why and you don't know what you can do to fix that," she says. "It's just devastating."

Melissa thought it was hopeless. Then her doctor called again. This time he asked if she'd be interested in trying something new. She and her husband hesitated at first.

"We eventually decided that we should give it one last shot," she says.

Her doctor is Dr. Robert Casper, the reproductive endocrinologist who...