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Four years ago, Scott Fahrenkrug saw an ABC News segment about the dehorning of dairy cows, a painful procedure that makes the animals safer to handle. The shaky undercover video showed a black-and-white Holstein heifer moaning and bucking as a farmhand burned off its horns with a hot iron.

Fahrenkrug, a molecular geneticist then at the University of Minnesota, thought he had a way to solve the problem. He could create cows without horns. He could save farmers money. And by eliminating the dairy industry’s most unpleasant secret, he might even score a public relations success for genetic engineering.

The technology Fahrenkrug believes could do all this is called genome editing (see “Genome Surgery” and “Genome Editing”). A fast, precise new way of altering DNA, it’s been sweeping through biotechnology labs. Researchers have used it to change the genes of mice, zebrafish, and monkeys, and it is being tested as way to treat human diseases like HIV (see “Can Gene Therapy Cure HIV?”).

With livestock, gene editing offers some extraordinary possibilities. At his startup, Recombinetics, located in St. Paul, Minnesota...