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Miguel Nicolelis, a top neuroscientist at Duke University, says computers will never replicate the human brain and that the technological Singularity is “a bunch of hot air.”

“The brain is not computable and no engineering can reproduce it,” says Nicolelis, author of several pioneering papers on brain-machine interfaces.

The Singularity, of course, is that moment when a computer super-intelligence emerges and changes the world in ways beyond our comprehension.

Among the idea’s promoters are futurist Ray Kurzweil, recently hired on at Google as a director of engineering and who has been predicting that not only will machine intelligence exceed our own but that people will be able to download their thoughts and memories into computers (see “Ray Kurzweil Plans to Create a Mind at Google—and Have It Serve You”).

Nicolelis calls that idea sheer bunk. “Downloads will never happen,” Nicolelis said during remarks made at the annual meeting of the American Association for the Advancement of Science in Boston on Sunday. “There are a lot of people selling the idea that you can mimic the brain with...