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Ten years ago a little girl from Colorado made medical history when her parents and her doctor at the University of Minnesota used genetic screening to create a baby that could save her life.

Now, 16 years old and back in Minnesota for her 10-year checkup, Molly Nash is unimpressed that her little brother -- her irritating little brother -- became a "savior sibling" by giving her his umbilical cord blood -- the sole reason she's alive today to back sass her parents.

Her parents, however, know what was at stake. Jack and Lisa Nash were offered a long-shot chance to save the life of their daughter and to have more children who did not have the fatal disease they both carry in their genes.

"I thank God every day that I have a 16-year-old to fight with," said Lisa Nash, who brought Molly to the university last week.

When their story first became public, reaction from around the globe ranged from astonishment to horror and helped fuel the backlash against embryonic research. Molly's doctor at the U, Dr. John...