Somatic gene transfer involves adding genes to cells other
than egg or sperm cells. If you had a lung disease caused by
a defective gene, scientists might be able to add a healthy
gene to your lung cells and alleviate the disease. The new gene
would not be passed to any children you may subsequently have.
The desired gene is attached to a viral vector, which
has the ability to carry the gene across the cell membrane.

Clinical trials of somatic gene transfers have been underway
since 1991. These attempts at somatic gene therapy have so far
produced very few successes and a number of serious adverse
results, including deaths.
But somatic gene transfer may eventually become an effective
treatment for at least some important medical conditions. Somatic
gene therapy should be evaluated according to the same criteria
as other medical procedures: safety, efficacy, accessibility,
and social implications.
However, somatic gene transfer techniques might also be proposed
for "enhancement" purposes. Some of these might be
inconsequential but others could be unacceptable and would need
to be proscribed. |